Table 1.
| Patient (age, gender) | Diagnosis | Number of Sequential BAL specimens Analyzed First Post Transplant Year | Number of Biopsies with Rejection | Cumulative Rejection Score | Number of PBMC analyzed first post transplant year | Included in 1 year of BAL analysis | Included in 1 year of PBMC analysis |
|---|---|---|---|---|---|---|---|
| 1. 48 M | Emphysema | 9 | 4 | 9 | 5 | Yes | Yes |
| 2. 59 F | Emphysema | 9 | 4 | 6 | 4 | Yes | No |
| 3. 57 M | Hypersensitivity Pneumonitis | 7 | 4 | 9 | 5 | Yes | Yes |
| 4. 38 M | Cystic Fibrosis | 7 | 2 | 4 | 4 | Yes | Yes |
| 5. 56 M | Idiopathic Pulmonary Fibrosis (IPF) | 7 | 4 | 8 | 6 | Yes | Yes |
| 6. 61 M | Emphysema | 5 | 1 | 1 | 3 | Yes | No |
| 7. 66 F | Emphysema | 7 | 0 | 0 | 6 | Yes | Yes |
| 8. 18 M | Cystic Fibrosis | 4 | 4 | 12 | 2 | No | No |
| 9. 22 M | Cystic Fibrosis | 8 | 6 | 11 | 7 | Yes | Yes |
| 10. 54 M | IPF | 8 | 5 | 8 | 6 | Yes | Yes |
| 11. 60 M | Emphysema | 9 | 1 | 1 | 9 | Yes | Yes |
| 12. 31 F | Cystic Fibrosis | 8 | 0 | 0 | 5 | Yes | Yes |
| 13. 18 F | Cystic Fibrosis | 5 | 2 | 4 | 5 | Yes | Yes |
| 14. 30F | Cystic Fibrosis | 6 | 2 | 4 | 5 | Yes | Yes |
| 15. 62M | IPF | 7 | 1 | 3 | 6 | Yes | Yes |
| 16. 40F | IPF | 7 | 3 | 4 | 6 | Yes | Yes |
| 17. 59M | IPF | 4 | 1 | 1 | 4 | No | No |
| 18. 63 M | IPF | 8 | 1 | 1 | 7 | Yes | Yes |
| 19. 60 M | IPF | 6 | 1 | 1 | 6 | Yes | Yes |
| 20. 63 F | IPF | 5 | 1 | 2 | 5 | Yes | Yes |
| 21. 64 M | IPF | 7 | 4 | 7 | 6 | Yes | Yes |
| 22. 60 F | Emphysema | 8 | 2 | 2 | 8 | Yes | Yes |
| 23. 16 M | Bronchiolitis Obliterans | 8 | 1 | 2 | 7 | Yes | Yes |
| 24. 51 F | IPF | 6 | 0 | 0 | 6 | Yes | Yes |
| 25. 48 M | IPF | 6 | 3 | 6 | 6 | Yes | Yes |
| 26. 60 M | Emphysema | 7 | 2 | 5 | 6 | Yes | Yes |
| 27. 61 M | Emphysema | 9 | 4 | 10 | 7 | Yes | Yes |
| 28. 62 M | Emphysema | 9 | 2 | 3 | 9 | Yes | Yes |
| 29. 56 M | Emphysema | 8 | 1 | 1 | 7 | Yes | Yes |
| 30. 46 M | Alpha-1 antitrypsin deficiency | 8 | 3 | 5 | 8 | Yes | Yes |
| 31. 52F | Emphysema | 7 | 2 | 2 | 6 | Yes | Yes |
| 32. 53F | Emphysema | 7 | 1 | 1 | 7 | Yes | Yes |
| 33. 51F | Sarcoidosis | 7 | 2 | 2 | 6 | Yes | Yes |
| 34. 63M | Emphysema | 7 | 0 | 0 | 5 | Yes | Yes |
| 35.54M | IPF | 7 | 1 | 2 | 6 | Yes | Yes |
| 36. 50F | Emphysema | 7 | 2 | 5 | 3 | Yes | No |
| 37. 60F | IPF | 7 | 0 | 0 | 7 | Yes | Yes |
| 38. 60M | IPF | 6 | 1 | 1 | 6 | Yes | Yes |
| 39. 56F | Emphysema | 4 | 0 | 0 | 4 | No | No |
| 40. 58F | IPF | 5 | 0 | 0 | 4 | No | No |
| 41. 59M | Emphysema | 4 | 0 | 0 | 3 | No | No |
| 42. 29F | Hypersensitivity Pneumonitis | 7 | 1 | 2 | 7 | No | No |
| 43. 66M | Emphysema | 6 | 2 | 4 | 6 | No | No |
| 44. 60M | IPF | 8 | 4 | 4 | 8 | No | No |
| 45. 44F | Emphysema | 4 | 0 | 0 | 4 | No | No |
| 46. 57M | AIP | 4 | 0 | 0 | 4 | No | No |
| 47. 61M | IPF | 4 | 2 | 4 | 3 | No | No |
| 48. 61F | Emphysema | 4 | 2 | 3 | 4 | No | No |
| 49. 48M | Emphysema | 4 | 0 | 0 | 4 | No | No |
| 50. 61M | IPF | 4 | 1 | 2 | 4 | No | No |
| 51. 17M | Cystic Fibrosis | 6 | 1 | 1 | 6 | No | No |
Demographics and clinical course of patients analyzed: The first 2 columns show patient age, gender and transplant indication. Also shown are the total number of BAL and PBMC samples analyzed, the total number of any degree of rejection in the first post transplant year and the cumulative rejection score. The final two columns indicate which patients had a year worth of sequential data to be included in the longitudinal analysis (figure 5).