Rat liver after CCl4 gavage. A: Rat liver [9 wk after T0 (12 wk after CCl4 gavage interruption)] extensive mutilating fibrosis, with nodules (cirrhosis). In the nodules separated by fibrous septa, hepatocytes with a basophil cytoplasm and a round nucleus are organized in fine spans (Masson's trichromie, × 10); B: Rat liver [6 wk after T0 (9 wk after CCl4 gavage interruption)] extensive mutilating fibrosis, with nodules (cirrhosis) (HE, × 10).