Fig. 3.

Aggregation kinetics of Aβ variants at low concentrations monitored by light scattering. (A) Representative light scattering intensity changes, ΔI_s (90°), vs. time for Aβ₄₀ (black), Aβ₄₂ (red), Aβ₄₀-1(2)^D1 (purple), Aβ₄₀-1(2)^K16 (green), and Aβ₄₀-1(2)^K28 (blue) at concentrations of 500 nM. (B) Representative ΔI_s (90°) vs. time for Aβ₄₀-1(2)^D1 (purple), Aβ₄₀-1(2)^K16 (green), and Aβ₄₀-1(2)^K28 (blue) at concentrations of 100 nM. Analogous data using concentrations <100 nM are shown in Fig. S2.