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Hairless Xpc+/− mice also transgenic for lacZ mutation-indicator gene were fed with vehicle or PL for 10 days and then were irradiated with a single dose of UVB (25 mJ/cm2). Two weeks after UVB, we evaluated mutation frequency (MF) in the lacZ mutation-indicator gene (seven to eight mice per treatment condition). Plotted values are MF per transgene in the harvested and homogenized epidermis (N = 7 to 8 per treatment group).
