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. 2009 Aug;161(2):419–426. doi: 10.1111/j.1365-2133.2009.09216.x

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Journal Compilation © 2009 British Association of Dermatologists

Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2.5, which does not permit commercial exploitation.

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Fig 2 — Application of the test product results in clinical improvement in facial wrinkles. (a) Clinical assessment identified a significant improvement (P=0·026) in wrinkle grade following treatment with the test product compared with the vehicle at 12 months, as ascertained by using a Monte Carlo simulation. Standardized photographs of the face of a 56-year-old woman at (b) baseline and (c) after 6 months’ application of the test product show an improvement in periorbital fine lines and wrinkles.