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Reversibility of CaMKII inhibition on arrythmogenicity of metabolic acidification. Representative recordings of epicardial MAPs from a Langendorff-perfused murine heart paced regularly at 8 Hz during exposure to metabolic acidification in the absence and presence of KN-93. (a) Control conditions with KN-93, (b) metabolic acidification with KN-93, (c) metabolic acidification after removal of KN-93 and (d) control conditions without KN-93.
