Table II.
Haematological parameters in SCD and non-SCD children.
| SCD |
non-SCD |
|||||
|---|---|---|---|---|---|---|
| Variable | Mean (SD) | N | Mean (SD) | N | Difference* (95% CI) | P value |
| Hb (g/l) | 73 (13) | 124 | 107 (14) | 262 | −34 (−37, −31) | <0·001 |
| Hct (%) | 23·1 (4·2) | 124 | 32·5 (3·9) | 262 | −9·4 (−10·2, −8·6) | <0·001 |
| MCV (fl) | 83·8 (10·9) | 124 | 74·7 (8·7) | 262 | 9·1 (6·9, 111·3) | <0·001 |
| MCHC (g/l) | 318 (12) | 124 | 329 (19) | 262 | −11 (−14, −8) | <0·001 |
| WBC (×109/l) | 19·2 (11·6) | 124 | 9·3 (3·5) | 262 | 9·9 (7·8, 12·0) | <0·001 |
| Platelets (109/l) | 386 (169) | 124 | 372 (156) | 262 | 14 (−49, 21) | 0·4354 |
| Reticulocytes (%) | 11·5 (6·7) | 119 | N/A | – | – | – |
Hb, haemoglobin; Hct, haematocrit; MCV, mean cell volume; MCHC, mean cell haemoglobin concentration; WBC, white blood cells.
*
Difference between means; a positive value implies value in SCD is greater, a negative value implies value in SCD is lower.