Fig. 3. Effect of transient Prx1 siRNA knockdown on DHT stimulation of AR activity in LNCaP cells.
Panel A, immunoblot of Prx1 in control and siRNA-transfected samples prepared for luciferase activity. Panel B, results of luciferase assay for AR transactivation in the presence of 0.1, 1 or 10 nM DHT. *P<0.05 compared to the corresponding control value.