Figure 4. Alignment of nuclear factor-κB essential modulator genomic DNA sequencing data: wild-type control (top), male patient (middle), and female carrier (bottom).
Male patient demonstrates one mutant NEMO allele and one pseudo-gene allele, whereas the female carrier demonstrates both wild-type and mutant NEMO alleles as well as two copies of the pseudogene. NEMO, nuclear factor-κB essential modulator.