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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Curr Opin Allergy Clin Immunol. 2009 Dec;9(6):517–524. doi: 10.1097/ACI.0b013e3283328f59

Figure 5. Alignment of genomic DNA sequencing data at the Fas exon 8 acceptor splice site: wild-type control (top), patient peripheral blood mononuclear cells (middle), and patient purified double-negative α/β T-cell receptor-positive T cells (bottom).

Figure 5

The mutant peak in the patient’s PBMCs is not distinguishable from baseline noise, and the mutation is only detectable in the chromatogram for the isolated DNTs. DNTs, double-negative α/β T cells; PBMCs, peripheral blood mononuclear cells.