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. Author manuscript; available in PMC: 2010 Sep 15.
Published in final edited form as: Virology. 2009 Jul 24;392(1):62–72. doi: 10.1016/j.virol.2009.06.048

Figure 2. Apoptotic activity of lp11w.

Figure 2

Figure 2

Figure 2

(A). Effect of Ad5 mutants on caspase activation. SCC25 cells were infected with indicated mutants and proteolytic processing of pro-caspase 3 and PARP were determined by western blot analysis. (B). Ultra-structure of infected cells. Thin sections of Ad-infected cells were analyzed by light microscopy (top panel) and by electron microscopy (bottom two panels). Apoptotic cells in the top panel of lp11w-infected samples are pointed out by arrows. (C). Flow cytometric analysis of annexin V-staining patterns of Ad-infected cells. The quantification of annexin V-positive and propidium iodide-positive cells is shown in the bar diagram.