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Model of graded release induced by amphipathic peptides. The peptides are unstructured in solution and form α-helices on the membrane, which are shown as viewed from one end of the helix. The dark half of the circle represents the hydrophobic face of the helix and the light half represents the hydrophilic face. Reproduced from ref. (5), as modified in ref. (4), with permission from Biophysical Journal. Copyright 2007 and 2009, respectively, Elsevier.
