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. 1999 Feb 20;318(7182):497–498. doi: 10.1136/bmj.318.7182.497

Table.

Isoniazid and multidrug resistance in isolates from patients with newly diagnosed tuberculosis in United Kingdom, 1994-6

All Isolates Isoniazid resistant
Multidrug resistant
No (%) 95% CI No (%) 95% CI
All 1994-6 10 142 599 (5.9) 5.5 to 6.4 152 (1.5) 1.3 to 1.8
Year:
 1994 3 253 181 (5.6) 4.8 to 6.4 43 (1.3) 1.0 to 1.8
 1995 3 254 197 (6.1) 5.3 to 7.0 49 (1.5) 1.1 to 2.0
 1996 3 635 221 (6.1) 5.3 to 6.9 60 (1.7) 1.3 to 2.1
Age (years):
 0-14   185   8 (4.3) 2.2 to 8.6  2 (1.1) 0.3 to 4.3
 15-44 4 792 389 (8.1) 7.3 to 9.0 95 (2.0) 1.6 to 2.4
 45-64 2 224 119 (5.4) 4.5 to 6.4 33 (1.5) 1.1 to 2.1
 ⩾65 2 492  58 (2.3) 1.8 to 3.0 17 (0.7) 0.4 to 1.1
 Unknown   449  25 (5.6) 3.8 to 8.2  5 (1.1) 0.5 to 2.7
Sex:
 Male 5 780 361 (6.2) 5.6 to 6.9 105 (1.8) 1.5 to 2.2
 Female 3 983 224 (5.6) 4.9 to 6.4 46 (1.2) 0.9 to 1.5
 Sex unknown   379  14 (3.7) 2.2 to 6.2  1 (0.3) 0.0 to 1.9
History of tuberculosis:
 Previous tuberculosis   568 107 (18.8) 14.8 to 21.6  64 (11.3)  8.4 to 13.7
 No known previous tuberculosis 9 574 492 (5.1) 4.7 to 5.6 88 (0.9) 0.7 to 1.1
Country in which diagnosed:
 England 8 731 546 (6.3) 5.8 to 6.8 140 (1.6) 1.4 to 1.9
 Northern Ireland   170   6 (3.5) 1.6 to 7.9  1 (0.6) 0.1 to 4.2
 Scotland   930  33 (3.5) 2.5 to 5.0  8 (0.9) 0.4 to 1.7
 Wales   311  14 (4.5) 2.7 to 7.6  3 (1.0) 0.3 to 3.0
Place of diagnosis:
 London 3 731 299 (8.0) 7.2 to 9.0 85 (2.3) 1.8 to 2.8
 Outside London 6 411 300 (4.7) 4.2 to 5.2 67 (1.0) 0.8 to 1.3
HIV infection:
 Positive   460  62 (13.5) 10.5 to 17.3 28 (6.1) 4.2 to 8.8
 Negative or unknown 9 682 537 (5.5) 5.1 to 6.0 124 (1.3) 1.1 to 1.5