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Hemolytic Activity of LLO
| EC50 (pM) |
|||
|---|---|---|---|
| Toxin | Reduced (pH 7.4) | Reduced (pH 5.5) | Oxidised (pH 7.4) |
| wtLLO | 21.9 ± 7 | 7 ± 0.3 | 10.9 × 103 ± 1.7 × 103 |
| E8C-LLO | 38 ± 7 | 5.6 ± 0.7 | 39.3 × 103 ± 11.7 × 103 |
| B3-LLO | — | — | 6.5 × 103 ± 1.2 × 103 |
EC50 values of the immunotoxin and isolated toxins in reduced and oxidized form in hemolysis under physiological (PBS, pH 7.4) and acidic (citrate, pH 5.5) conditions.
