Table 3. List of genes obtained by paired analysis and gcRMA normalization.
|
Treatment 30 min |
||
|
Gene ID |
FC |
Gene title |
|
Transcription regulator (3) |
||
| 13653 |
-1.65 |
early growth response 1 (Egr-1) |
| 22141 |
1.51 |
tubby homolog (mouse; Tub) |
| 17260 |
1.63 |
MADS box transcription enhancer factor 2, polypeptide C (Mef2c) |
|
Transporter (3) |
||
| 73836 |
1.53 |
solute carrier family 35, member B2 (Slc35b2) |
| 18824 |
2.00 |
proteolipid protein 2 (colonic epithelium-enriched; Plp2) |
| 224022 |
2.26 |
solute carrier family 7, member 4 (Slc7a4) |
|
Transmembrane receptor (1) |
||
| 22288 |
1.59 |
utrophin (homologous to dystrophin; Utrn) |
|
Peptidase (1) |
||
| 69617 |
-1.55 |
pitrilysin metallopeptidase 1 (Pitrm1) |
|
Enzyme (3) |
||
| 545195 |
1.50 |
cytochrome P450, family 4, subfamily f, polypeptide 16 (Cyp4f16) |
| 69719 |
1.70 |
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (Cad) |
| 54616 |
1.72 |
exostoses (multiple)-like 3 (Extl3) |
|
Other (4) |
||
| 26936 |
-1.58 |
myosin phosphatase-Rho interacting protein (m-Rip) |
| 57908 |
1.52 |
zinc finger protein 318 (Zfp318) |
| 320165 |
1.52 |
transforming, acidic coiled-coil containing protein 1 (Tacc1) |
| 320295 |
1.58 |
RIKEN cDNA C920006O11 gene (C920006O11Rik) |
|
Unknown (1) |
||
| 1427797_s_at |
1.62 |
|
|
Treatment 4 h |
||
|
Gene ID |
FC |
Gene title |
|
Transcription regulator (5) |
||
| 13653 |
-2.20 |
early growth response 1 (Egr1) |
| 14281 |
-2.05 |
FBJ murine osteosarcoma viral oncogene homolog (cFos) |
| 225872 |
-1.91 |
neuronal PAS domain protein 4 (Npas4) |
| 21418 |
-1.52 |
transcription factor AP-2 alpha (Tcfap2a) |
| 21677 |
1.56 |
TEA domain family member 2 (Tead2) |
|
Transporter (1) |
||
| 317717 |
-1.59 |
SEC22 vesicle trafficking protein homolog A (S. cerevisiae; Sec22l2) |
|
Peptidase (1) |
||
| 72344 |
1.61 |
ubiquitin specific peptidase 36 (Usp36) |
|
Kinase (1) |
||
| 56637 |
-1.52 |
glycogen synthase kinase 3 beta (Gsk3b) |
|
Enzyme (2) |
||
| 12662 |
-1.74 |
choroideremia (Rab escort protein 1; Chm) |
| 78797 |
-1.52 |
NADPH dependent diflavin oxidoreductase 1 (Ndor1) |
|
Other (14) |
||
| 19707 |
-2.27 |
RALBP1 associated Eps domain containing 1 (Reps1) |
| 68607 |
-2.01 |
serine hydrolase-like 2 (Serhl) |
| 67785 |
-1.95 |
zinc finger, MYM-type 4 (Zmym4) |
| 22289 |
-1.71 |
ubiquitously transcribed tetratricopeptide repeat, X chromosome (Utx) |
| 104910 |
-1.63 |
chromosome 14 open reading frame 68 (C14ORF68) |
| 67974 |
-1.56 |
chromosome 10 open reading frame 9 (C10ORF9) |
| 15982 |
-1.53 |
interferon-related developmental regulator 1 (Ifrd1) |
| 70828 |
-1.53 |
RIKEN cDNA 4633401B06 gene (4633401B06Rik) |
| 109200 |
-1.51 |
RIKEN cDNA A430102J17 gene (A430102J17Rik) |
| 77656 |
-1.51 |
RIKEN cDNA C430045I18 gene (C430045I18Rik) |
| 216971 |
-1.51 |
chromosome 17 open reading frame 63 (C17ORF63) |
| 320003 |
-1.50 |
RIKEN cDNA C430014K11 gene (C430014K11Rik) |
| 78893 |
1.53 |
CCR4-NOT transcription complex, subunit 10 (Cnot10) |
| 52710 |
1.54 |
G protein-coupled receptor 172A (Gpr172b) |
| Unknown (3) |
||
| 1443057_at |
-2.41 |
|
| 1446932_at |
-1.83 |
|
| 1444274_at |
-1.60 |
|
|
Treatment 6+6 h |
||
|
Gene ID |
FC |
Gene title |
|
Transcription regulator (2) |
||
| 13653 |
-1.77 |
early growth response 1 (Egr1) |
| 109115 |
-1.67 |
suppressor of Ty 3 homolog (S. cerevisiae; Supt3h) |
|
Transporter (1) |
||
| 224022 |
-1.55 |
solute carrier family 7, member 4 (Slc7a4) |
|
Enzyme (5) |
||
| 74335 |
-1.90 |
X-ray repair complementing defective repair inChinese hamster cells 3 (Xrcc3) |
| 50505 |
-1.69 |
excision repair cross-complementing rodent repair deficiency, complementation group 4 (Ercc4) |
| 19361 |
-1.68 |
RAD51 homolog (RecA homolog, E. coli; S. cerevisiae; Rad51) |
| 13804 |
-1.68 |
endonuclease G (Endog) |
| 242202 |
1.64 |
phosphodiesterase 5A, cGMP-specific (Pde5a) |
|
Other (12) |
||
| 627191 |
-1.87 |
transmembrane protein 90a (Tmem90a) |
| 237781 |
-1.52 |
Smith-Magenis syndrome chromosome region, candidate 7 (Smcr7) |
| 76073 |
-1.51 |
polycomb group ring finger 5 (Pcgf5) |
| 19650 |
-1.51 |
retinoblastoma-like 1 (p107; Rbl1) |
| 210766 |
1.55 |
BRCA1/BRCA2-containing complex, subunit 3 (Brcc2) |
| 238130 |
1.56 |
dedicator of cytokinesis 4 (Dock4) |
| 20324 |
1.58 |
serum deprivation response (phosphatidylserine binding protein; Sdpr) |
| 320191 |
1.61 |
hook homolog 3 (Drosophila; Hook3) |
| 67693 |
1.61 |
Huntingtin interacting protein K (Hypk) |
| 19359 |
1.65 |
RAD23 homolog B (S. cerevisiae; Rad23b) |
| 211550 |
1.69 |
TRAF-interacting protein with a forkhead-associated domain (Tifa) |
| 73126 |
1.72 |
RIKEN cDNA 3110038A09 gene (3110038A09Rik) |
|
Unknown (1) |
||
| 1440123_at | 1.61 |
"Entrez gene" accession numbers or Affymetrix ID (Gene ID), fold changes (FC) and names of the genes that were differentially expressed in the diffuser covered eyes relative to the ND filter treated control eyes are displayed. A p<0.05 was considered significant. Genes chosen for validation are colored in red.