Table 4.
Regression coefficients and 95% CIs for urinary 8-OHdG concentrations regressed on 12-hour-average PM2.5 concentrationsa
| Including all data points | Excluding outlying data pointsb | |||||||
|---|---|---|---|---|---|---|---|---|
| Coefficient (95% CI) | p-value | Coefficient (95% CI) | p-value | |||||
| Crude association | −0.40 | (−0.79, −0.01) | p = | 0.04 | −0.33 | (−1.35, 0.69) | p = | 0.51 |
| Adjusted association c | −0.51 | (−0.95, −0.07) | p = | 0.02 | −0.69 | (−1.74, 0.36) | p = | 0.19 |
| Effect modification by hypertension status v | ||||||||
| Hypertensives | −0.60 | (−1.03, −0.17) | p = | 0.01 | −1.36 | (−2.54, −0.19) | p = | 0.02 |
| Non-hypertensives | 1.10 | (−0.68, 2.88) | p = | 0.22 | 1.08 | (−0.71, 2.86) | p = | 0.23 |
a
Coefficient is expressed as the change in urinary 8-OHdG concentration (μg/g creatinine) per 10 μg/m3 increase in PM2.5.
b
Two outlying data points, both from the same hypertensive individual, were excluded in these analyses.
c
Models adjusted for age, gender, current smoking status, and time of day