Fig. 6.

In vitro effects of matrine (MA) on the excretion of VEGF-A in A549 cells. The cells were treated for 24 h with matrine at concentrations of 50–500 μg/mL. Then each supernatant of the cell culture was respectively collected and analyzed by using an ELISA kit (VEGF-A) as described in the section of “Materials and methods”. Values are shown as mean ± SD (bar) for the indicated concentration (n = 3). The figure is the representative of 3 similar experiments. Statistical analysis was carried out using the one-way ANOVA followed by Bonferroni post hoc test. * P < 0.05.; ** P < 0.01