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. 1998 May 26;95(11):6403–6407. doi: 10.1073/pnas.95.11.6403

Figure 2.

Figure 2

Inhibition by MC148P of CC and CXC chemokine-induced migration of human monocytes, neutrophils, and lymphocytes. Cell migration was determined by using a modified Boyden chamber. Additions to the lower well are indicated below each bar. Each condition was tested in triplicate, and the data are presented as the mean ± SE. The percentage of cell migration was determined from the ratio of the number of cells on the underside of the filter (in five 40× fields) in the presence of chemokine and indicated concentrations of MC148P, and the number of cells on the underside of the filter in the presence of chemokine alone (in five 40× fields). Each experiment was performed at least three times, and results from representative ones are shown. The average number of cells and the calculated SEM counted in the absence of MC148P were: MCP-1, 533 ± 98; MCP-3, 502 ± 19; fMLF, 165 ± 15; IL-8, 305 ± 15; RANTES, 169 ± 11; MIP-1α, 217 ± 25; SDF-1 (lymphocytes), 877 ± 37; SDF-1 (monocytes), 276 ± 45; I-309, 571 ± 37.