Table 1.
South Africa | Zambia | Tanzania | Uganda | |||
Durban | Joburg | Africa Centre sites | Mazabuka | Mwanza+ | Masaka* | |
Populations | Health clinics and associated communities | Recreational facilities | Sero-discordant couples | |||
Start date | Aug 02 | Oct 02 | Jul 03 | Mar03 | Mar 03 | Oct 03 |
N screened | 1263 | 1088 | 882 | 1974 | 1573 | 1370 |
% HIV +ve at screen | 47% | 20% | 50% | 30% | 25% | 7% |
% pregnant at screen | 1% | 4% | 1% | 4% | 10% | - |
N enrolled | 608 | 757 | 453 | 590 | 1573 | 50 |
% of enrolled seen at FU or later† | ||||||
3 m | 94% | 84% | 63% | 87% | 83% | 90% |
6 m | 88% | 79% | 56% | 79% | 79% | 84% |
9 m | 82% | 83% | 56% | 70% | 70% | 86% |
12 m | 67% | 87% | 58% | 63% | 71% | 86% |
Recruitment period (months) | 14 | 15 | 12 | 18 | 14 | 2 |
Person years FU | 499.2 | 531.4 | 158.1 | 356.4 | 717.4 | 31.2 |
Sero-conversions | 37 | 21 | 20 | 13 | 25 | 4 |
HIV incidence | 7.4 | 3.9 | 12.6 | 3.6 | 3.5 | 12.6 |
95%CI | 5.4, 10.2 | 2.6, 6.1 | 8.2, 19.6 | 2.1, 6.3 | 2.4, 5.2 | 4.8, 34.1 |
†follow-up rates based on % of 3 month attendees who returned subsequently; +All 1573 women were enrolled in Mwanza but the HIV incidence calculation was based on those who were HIV negative at enrolment;*sero-discordant couples enrolled