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. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: J Immunol. 2009 Sep 4;183(7):4467–4474. doi: 10.4049/jimmunol.0901428

FIGURE 7.

FIGURE 7

Reduced expression levels of granzyme B and CD27 during the secondary response in the absence of ThPOK. A, Five days after the secondary LCMV challenge, spleen cells from rechallenged mice were stimulated in vitro with GP33 peptide for 5 h. The production of IFN-γ and TNF-α in ThPOKhd/hd or ThPOKwt/wt P14 cells are shown. B, Granzyme B expression levels of ThPOKhd/hd (shaded histogram) or ThPOKwt/wt (open histogram) P14 cells in the spleen 5 days after rechallenge were analyzed. C, CD27 expression on ThPOKhd/hd P14 (shaded histogram) or ThPOKwt/wt P14 cells (open histogram) 7 days after rechallenge was analyzed by flow cytometry. Results are representative of two independent experiments.