Figure 3. Neurons mediating response to ascr#3.
a,Dose-response curve for male reversal rates on plates with increasing concentrations of ascr#3. n≥15 animals for each histogram. Error bars, s.e.m.; *P<0.05, **P<0.01, one-factor analysis of variance with post test. b, Male attraction by ascr#3 in sensory-deficient mutants17-19. Error bars, s.e.m. c, General sensory neurons and sex-specific neurons mediate response to ascr#3. Ablation of neurons involved in volatile chemotaxis (amphid winged sensory neuron type A (AWA) and amphid winged sensory neuron type C (AWC)) together with the CEM neurons6 did not affect response to ascr#3, in comparison with animals lacking only CEM neurons. n≥15 animals for each ablation set. Error bars, s.e.m.;*P<0.05, **P<0.01, one-factor analysis of variance with post test.