Figure 1.
Protein fold and relative orientation of the A and B chain monomers of AppA forming the noncrystallographic dimer. The C-terminal helix and tail are not part of the BLUF domain. (A) Stereo ribbon diagram including models for the flavin cofactor and two detergent molecules. (B) The dimer in a slightly different orientation with the molecular surface color-coded according to electrostatic potential, red denoting negative and blue positive. The apparent hole between monomers is the location of the partially ordered detergent molecule shown in panel A.