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. Author manuscript; available in PMC: 2009 Nov 9.
Published in final edited form as: Neuropharmacology. 2008 Apr 23;55(1):47–54. doi: 10.1016/j.neuropharm.2008.04.010

Fig. 2. mGlu5 receptor antagonists increased GPSP rate.

Fig. 2

A: Application of the selective mGlu1 receptor antagonist LY 367385 (100 µM) did not affect the rate of ongoing GPSPs. B: Application of the selective mGlu5 receptor antagonist MPEP (10 µM) increased the rate of ongoing GPSPs, which then decreased with washout of the MPEP. C: Application of the potent and selective mGlu5 receptor antagonist MTEP (500 nM) increased the rate of GPSPs, which then decreased with washout of the MTEP. * indicates statistically significantly different from control; NS indicates not statistically significantly different from control.