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. Author manuscript; available in PMC: 2010 Jun 3.
Published in final edited form as: J Am Chem Soc. 2009 Jun 3;131(21):7293–7303. doi: 10.1021/ja805174z

Scheme 1.

Scheme 1

Initial strategy for synthesis of fluorescent prenylated peptides labeled via FITC modification. Although 8 elutes as a single peak in HPLC analysis, it is likely that it is an isomeric mixture of the structure shown and is the isomer containing the farnesyl group on the thiourea sulfur atom.