Table 4.
Changes of 17 loci during in vitro serial passages
| Locus | Number of passages that showed a change1) | Change of the TRs copy number | |||
|---|---|---|---|---|---|
|
B. abortus 544 |
B. abortus 2308 |
B. abortus KBa019 |
B. abortus KBa011 |
||
| Bruce 04 | 28 | - 2) | - | - | An increase in one TRs |
| Bruce 16 | 28 | - | - | - | An increase in one TRs |
| Hoof 3 | 29 | - | - | - | An increase in one TRs |
| 14 other loci | - | - | - | - | none |
1) Four strains were sub-cultured to fresh media 30 times by serial passages at two- to three-day intervals
2) No change after 30 passages