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Bone Marrow-Derived GFP+ Fibrocytes in the Lung during Bleomycin-Induced Pulmonary Fibrosis
| Fibrocytes | Saline [cells/lung (×106)] | Bleomycin [cells/lung (×106)] |
|---|---|---|
| CD45+Col1+ | 1.5 ± 0.09 | 3.3 ± 0.12 |
| CD45+Col1+GFP+ | 0.97 ± 0.2 | 2.26 ± 0.15 |
| CD45+Col1+GFP– | 0.48 ± 0.1 | 1.1 ± 0.48 |
A larger population (CD45+Col1+GFP+) and a smaller population (CD45+Col1+GFP–) are found in the lungs of chimeric mice at Day 8 after exposure to bleomycin.
