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Bone Marrow-Derived GFP+ Fibrocytes in the Bone Marrow during Bleomycin-Induced Pulmonary Fibrosis
| Fibrocytes | Saline [cells/BM (×105)] | Bleomycin [cells/BM (×105)] |
|---|---|---|
| CD45+Col1+ | 0.95 ± 0.08 | 3.7 ± 0.12 |
| CD45+Col1+GFP+ | 0.92 ± 0.09 | 3.2 ± 0.2 |
| CD45+Col1+GFP– | 0.03 ± 0.001 | 0.5 ± 0.015 |
A larger population (CD45+Col1+GFP+) and a smaller population (CD45+Col1+GFP–) are found in the bone marrow (BM) of chimeric mice at Day 8 after exposure to bleomycin.
