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. Author manuscript; available in PMC: 2010 May 12.
Published in final edited form as: Curr Biol. 2009 Mar 26;19(9):758–763. doi: 10.1016/j.cub.2009.03.018

Figure 2. Injection of α-ICIS antibodies (AB) into cells gives a monopolar spindle phenotyope.

Figure 2

A. ICIS D antibodies inhibit Kif2a reactivation in vitro. Quantification of the mean number of microtubules per field in the presence of recombinant Kif2a, Aurora B, ICIS D, and α-ICIS. Error bars represent standard deviation.

B. IgG control-injected and α-ICIS injected in prophase Xenopus S3 cells expressing GFP-tubulin. Time lapse images from Supplemental movies 1 and 2. 0 minutes=time of injection. Scale bar represents 10μm.