Skip to main content
. Author manuscript; available in PMC: 2009 Nov 10.
Published in final edited form as: J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Jan 16;863(1):107–114. doi: 10.1016/j.jchromb.2008.01.001

Table 1.

Tandem Mass Spectrometry Parameters for Nicotine and Metabolites in Meconium

Period 1
Q1
Mass
(amu)		 Q3
Mass
(amu)		 Dwell
Time
(msec)		 DPa
(volts)		 Entrance
Potential
(volts)		 CEPb
(volts)		 Collision
Energy
(volts)		 CXPc
(volts)
OH-cotinined 193.2 80.2* 150 46 8.5 14.00 35 8
193.2 134.1 150 46 8.5 14.00 25 8
OH-cotinine-D3 196.2 80.2* 150 46 12.0 14.00 39 6
196.2 134.0 150 46 12.0 14.00 27 6
Cotinine 177.2 80.0* 150 41 3.0 12.00 37 4
177.2 98.2 150 41 3.0 12.00 25 4
Cotinine-D3 180.2 80.0* 150 36 3.0 14.00 31 4
180.2 101.2 150 36 3.0 4.00 27 4
Norcotinine 163.2 80.2* 150 51 10.0 10.00 33 6
163.2 118.1 150 41 10.0 10.00 29 6
Norcotinine-D4 167.2 84.2* 150 46 10.5 12.00 33 6
167.2 139.2 150 46 10.5 12.00 27 6
Nornicotine 149.2 80.2* 150 36 4.5 12.00 27 4
149.2 130.1 150 36 4.5 12.00 25 4
Nornicotine-D4 153.25 134.1 150 36 4.5 14.43 27 4
153.25 84.1* 150 36 4.5 14.43 29 4
Period 2
Nicotine 163.2 84.2* 250 36 4.5 12.00 29 8
163.2 132.0 250 36 5.5 12.00 21 6
Nicotine-D4 167.2 136.0* 250 36 6.0 10.00 21 4
167.2 121.2 250 36 6.0 10.00 35 6
*

Denotes quantifier transition

a

Declustering Potential

b

Collision Entrance Potential

c

Cell Exit Potential

d

trans-3’-Hydroxycotinine