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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Gastroenterology. 2009 May 13;137(2):649–659.e2. doi: 10.1053/j.gastro.2009.05.004

Figure 2.

Figure 2

DCAMKL-1 is essential for tumor growth. (A) HCT116 cells were injected into the flanks of athymic nude mice (n=5 per group) to generate tumors. At day 15 siRNAs (si-DCAMKL-1 and si-Scr) were injected directly into the tumors and followed by injections every third day (inset). After 5 injections, tumors were excised at day 28 and are represented above. Tumor sizes with standard error are shown from data collected at the time of every injection. (B) si- DCAMKL-1 treatment resulted in significantly decreased tumor weight when compared to controls. (C) The expression of DCAMKL-1 mRNA in the tumors quantitated by real-time RT-PCR. (D) Western blot analysis for DCAMKL-1 was performed on tumors samples as indicated. For A – C, values are given as average ± SEM and * denote statistically significant differences (*p<0.01) compared to control.