Effect of first-layer μa mismatch between the reference site and the target site on the reconstructed image. First-layer optical properties at the target and reference sites are (a) μa1_tar=0.023, μa1_ref=0.023; (b) μa1_tar=0.04, μa1_ref=0.023; (c) μa1_tar=0.04, μa1_ref=0.04; and (d) μa1_tar =0.023, μa1_ref=0.04. The other background optical properties of both the reference and target sites are , μa2=0.08, and . The optical properties of the target are μa=0.23 and .