Table 1.
Colony formation stimulated by SCF, TPO, or IL-5
| Stimulus | Mean number of colonies
|
|||||
|---|---|---|---|---|---|---|
| Bl | G | GM | M | Eo | Meg | |
| SCF | 10 | 47 | 2 | 3 | – | – |
| TPO | – | – | – | – | – | 5 |
| IL-5 | – | – | – | – | 9 | – |
| SCF + TPO | 10 | 44 | 3 | 2 | – | 13 |
| SCF + IL-5 | 9 | 48 | 3 | 2 | 13 | – |
Figures are mean colony counts in duplicate 7-day cultures of 50,000 C57BL bone marrow cells stimulated by 100 ng of SCF, 50 ng of TPO, 10 ng of IL-5, or the latter factors combined with SCF, Bl, blast cell; G, granulocytic; GM, granulocyte–macrophage; M, macrophage; Eo, eosinophilic; Meg, megakaryocytic colonies.