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β2 adrenergic receptor structure with inserted T4 lysozyme domain. T4 lysozyme (dark blue) was inserted in the loop between TM segments 5 and 6 of the β2 adrenergic receptor (light blue) to aid crystallization by adding potential crystal contacts and reducing conformational heterogeneity. The bound antagonist, carazolol, and cholesterol are shown in stick representation. An interactive view is available in the electronic version of the article.
