Figure 3.

Effect of different radial distance ranges upon the discrimination between native and near-native protein structures by energy functions defining effective atomic interactions. Eight empirical potentials were derived for four maximum distance range values (5.0, 7.0, 12.0, 15.0 Å) and two Ω values (90° and 180°). Combinations at both derivation and evaluation parameters were used to evaluate the discrimination of native structures from their near-native counterparts. Black bars indicate the performance of the potential derived and used as a canonical scoring function (D_π-U_π). Dark gray bars indicate the effective potential at derivation and evaluation (D₉₀-U₉₀). Light gray bars show the performance of the potentials derived cannonically but used effectively (D_π-U₉₀). Finally, the results of using the combination D₉₀-U_π are shown in white bars.