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. 2009 Nov;331(2):404–411. doi: 10.1124/jpet.109.156877

Fig. 3.

Fig. 3.

Anti-PECAM/catalase, but not anti-PECAM/SOD, protects lungs against I/R. Mice were anesthetized and received intravenous injections of equimolar doses of catalase or SOD conjugates 30 min before left pulmonary artery clamping. Animals were subjected to ischemia (1 h) and then reperfusion (1 h) of the left lung. A, BAL proteins shown as percentage of protection versus sham-operated animals calculated as described in Materials and Methods. B, blood oxygenation in animals preinjected with conjugates. Upper and lower dash lines indicate blood oxygenation in sham and untreated I/R groups, respectively. #, P < 0.05, conjugate-treated group versus control I/R group; *, P < 0.05, anti-PECAM group versus control IgG group.