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Effects of hypoxia on TI (A), TE (B), phrenic burst frequency (C), and ∫Phr burst amplitude (D). Both TI and TE were reduced, and burst frequency was enhanced during hypoxia. ∫Phr amplitude showed a progressive increase as hypoxia progressed. After hypoxia, TE was elongated, resulting in a decrease of phrenic burst frequency. ∫Phr amplitude was maintained above baseline at 3 min after hypoxia. *P < 0.05 and **P < 0.01 vs. baseline.
