Skip to main content
. Author manuscript; available in PMC: 2009 Nov 10.
Published in final edited form as: Nature. 2008 Jul 30;455(7209):128–132. doi: 10.1038/nature07188

Figure 4. A scheme of tight coupling pathway of myosin-V.

Figure 4

The mechanism shown by intermediates (1) through (4) is the main pathway of stepping during a MyoV-HMM processive run. Termination of runs would occur via pathway (1) to (A) to (B) or more rarely by (C) to (D) to (E) to (A) to (B). Red spots represent ADP and green spots represent Pi.