Table 2.
Menarche, Menopause, and Angiographic Coronary Disease
| No CAD(n = 482) | CAD(n = 164) | pa | |
|---|---|---|---|
| Menarche age (years ± SD) | 12.6 ± 1.8 | 12.9 ± 1.8 | 0.38 |
| Regular periods (%) | 80 | 84 | 0.53 |
| Number of pregnancies (±SD) | 3.6 ± 2.3 | 3.8 ± 2.9 | 0.50 |
| Prior OC use (%) | 44 | 26 | 0.08 |
| Years of OC use (years ± SD) | 2.0 ± 4.2 | 1.2 ± 3.4 | 0.34 |
| Menopausal age (years ± SD) | 44 ± 8 | 46 ± 8 | 0.36 |
| Years since final menstrual period (years ± SD) | 16.0 ± 9.8 | 19.5 ± 10.2 | 0.36 |
| Menopausal symptoms (%) | 72 | 54 | 0.002 |
| Any gynecological surgery (%) | 70 | 46 | <0.0001 |
| BO (%) | 41 | 23 | 0.002 |
| BO before age 55 years (%) | 38 | 22 | 0.01 |
| Hysterectomy only (%) | 19 | 17 | 0.27 |
| Hysterectomy only before 55 years (%) | 18 | 15 | 0.35 |
| Hysterectomy with or without UO/BO prior to age 55 years (%) | 64 | 42 | 0.0004 |
a
All p-values are age-adjusted, except age.
OC, oral contraceptive; BO, bilateral oophorectomy; CAD, coronary artery disease; SD, standard deviation; UO, unilateral oophorectomy.