Table 1.

Effect of galardin on embryonic and perinatal lethality in wild-type and plasminogen-deficient mice

	Number of pregnant mice	Mice that delivered pups	Total number of pups*	Average number of pups/pregnant mouse	Number of resorptions	Twenty-four hour survival of pups	Average number of pups/pregnant mouse surviving 24 hours
Plg+/+ + mock	7	100% (7)	43	6.2	0	100%	6.2
Plg−/− + mock	7	100% (7)	49	7.0	0	100%	7.0
Plg+/+ + galardin	6	83% (5)	44†	7.3	9	42%	3.1
Plg−/− + galardin	8	25% (2)	16‡	2.0	41	38%	0.8

^*Includes fully developed pups born plus pups remaining in the uterus.

^†Eight of these pups remain in the uterus of two mice 24 hours after birth of the first pups.

^‡Eight of these pups remain in the uterus of four mice 24 hours after birth of the first pups.