Table 4. Summary of results for single marker genome scans for post-prandial glucose.
| Chromosome | Peak Marker (position in cM) | LOD | Locus Name | Homology/Relevant Overlapping QTL | Genes identified in human GWAS |
|---|---|---|---|---|---|
| 1 | D1Rat145 (136) | 3.54** | Gluco51 | Niddm1, 7, 16, 24, 35, 44, 64, 65, 66 (Chung et al. 1997; Fakhrai-Rad et al. 2000; Galli et al. 1999; Galli et al. 1996; Gauguier et al. 1996; Granhall et al. 2006; Kanemoto et al. 1998; Lin et al. 2001; Wei et al. 1999) | TCF7L2, HHEX-IDE (Lango et al. 2008) |
| 5 | D5Rat157 (70) | 2.61* | Gluco52 | Niddm30 (Sugiura et al. 1999); | CDKN2A/2B (Lango et al. 2008) |
| 7 | D7Rat24 (46) | 3.09* | Gluco53 | Niddm19 (Kose et al. 2002; Wei et al. 1999); Sradr-5 (Solberg et al. 2006) | SLC30A8, TSPAN8/LGR5 (Lango et al. 2008) |
| 9 | D9Rat130 (20) | 2.81* | Gluco54 | Niddm26 (Wei et al. 1999); Imm-5 (Solberg et al. 2004) | |
| 18 | D18Rat121 (44) | 2.31* | Gluco55 |
suggestive threshold (37%) is 2.13
significant threshold (95%) is 3.43