. Author manuscript; available in PMC: 2009 Nov 10.

Published in final edited form as: Virchows Arch. 2008 Sep 13;453(4):387–400. doi: 10.1007/s00428-008-0658-x

Table 2.

Histopathological findings
	Preterm and term controls	Preterm preeclampsia	Preterm HELLP	Term preeclampsia
Number of placentas¹ (n)	14	9	10	5
Distal villous insufficiency (%)	0	55.6^†	50^†	40^‡
Increased syncytial knots (%)	57.2	88.9	70	100
Increased perivillous fibrin (%)	0	55.6^†	20	40^‡
Recent villous infarct (%)	0	55.6^†	30^‡	0
Remote villous infarct (%)	7.2	33.4	70^†	40
Remote villous infarct, extensive (%)	7.2	44.4^‡	80^*	40
Small placenta (%)	0	66.7^*	66.7^*	60^†
Uteroplacental vessel thrombosis (%)	0	22.3	55.6^†	0
Uteroplacental vessel adaptation problem² (%)	0	25	44	25
Villous stromal fibrosis (%)	7.2	66.7^†	60^†	60^‡
Villous dysmaturity (%)	7.2	77.8^†	80^*	40

Three macroscopically normal central and paracentral areas of the placental discs, an en face block of the basal plates, and all blocks of the macroscopic lesions were microscopically evaluated in each placenta.

Fibrinoid necrosis with or without acute atherosis.

The Pearson's chi-square test and the Fisher's exact test were used for statistical analysis.

Values are presented as number or percentage.

p<0.001

^†

p<0.01

^‡

p<0.05 compared to controls.