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. Author manuscript; available in PMC: 2009 Nov 10.
Published in final edited form as: Nature. 2008 Sep 24;455(7217):1244–1247. doi: 10.1038/nature07344

Figure 1.

Figure 1

Growth of L. monocytogenes is decreased in GILT-deficient mice and GILT-deficient macrophages. a, In vivo colony counts of L. monocytogenes (strain 10403s) injected intravenously in wild type B6 or GILT-deficient mice. At each time point three mice per group were sacrificed and spleens and livers were harvested each day for bacterial colony counts to obtain CFU/gram. A representative of three individual experiments is shown. b, In vitro growth of L. monocytogenes in bone marrow-derived macrophages from wild type B6 and GILT-deficient mice. The cells (106 per well) were lysed at each time point shown and plated to obtain the CFU. A representative of three individual experiments is shown. Statistically significant differences with a p < 0.05 are indicated by *, and with a p < 0.01 by **.