Table 3.

Regression analyses on factors associated with % predicted FEV1 at age 6 years

	regression coefficient	P-value
Univariate regression with %FEV1 as the response variable
Responder (vs. non-responder)	+11.2	0.015
Growth during age 2 to 6 (vs. “maintained”)	+6.9 (“lessened”)	0.280
	−7.6 (“unchanged”)	0.167
	−13.3 (“improved”)	0.050
SA positive at age 2 (vs. negative)	−7.9	0.141
SA positive at age 6 (vs. negative)	+1.2	0.798
PA positive at age 2 (vs. negative)	−0.7	0.898
PA positive at age 6 (vs. negative)	−4.3	0.362
PA positive during age 2 to 6 (vs. never)	+0.1 (transient)	0.981
	−8.4 (intermittent)	0.319
	−2.2 (persistent)	0.741
Brasfield CXR at age 2	+1.7	0.170
Wisconsin CXR at age 2	−0.4	0.438
Brasfield CXR at age 6	+1.2	0.367
Wisconsin CXR at age 6	−0.5	0.256
Mean Brasfield CXR during age 2 to 6	+2.1	0.135
Mean Wisconsin CXR during age 2 to 6	−0.7	0.193
Multiple regression with %FEV1 as the response variable
Model 1: adjusting for PA and SA
Responder (vs. non-responder)	+10.9	0.019
SA positive at age 2 (vs. negative)	−5.7	0.272
PA positive at age 6 (vs. negative)	−5.4	0.235
Model 2: adjusting for CXR
Responder (vs. non-responder)	+10.0	0.041
Mean Brasfield CXR during age 2 to 6	+1.0	0.475
Model 3: adjusting for both PA and CXR
Responder (vs. non-responder)	+9.9	0.046
SA positive at age 2 (vs. negative)	−5.7	0.281
PA positive at age 6 (vs. negative)	−5.1	0.268
Mean Brasfield CXR during age 2 to 6	+0.8	0.582
Logistic regression with %FEV1 < 5th percentile (i.e., < 82.5%) as the response variable
Model 4: adjusting for both PA and CXR
Responder (vs. non-responder)	0.09 (0.02, 0.44)*	0.003
SA positive at age 6 (vs. negative)	1.63 (0.32, 8.24)*	0.557
PA positive at age 6 (vs. negative)	1.42 (0.29, 6.84)*	0.664
Mean Brasfield CXR during age 2 to 6	1.05 (0.89, 1.23)*	0.851

^*odds ratio and 95% confidence interval