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. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Eur J Pharmacol. 2009 Apr 1;607(1-3):251–257. doi: 10.1016/j.ejphar.2009.01.042

Figure 1.

Figure 1

Arterial blood glucose and hepatic glucose loads in 42-h-fasted conscious dogs during the basal (−30–0 min) and experimental periods (period [P] 1, 0–90 min; P2, 90–270 min). Somatostatin was infused peripherally and insulin (4-fold basal) and glucagon (basal) were given intraportally, while glucose was delivered peripherally at a variable rate to increase the hepatic glucose load 2-fold basal during P1 and P2. SAL group (n=11), received intraportal normal saline during P2; L-ESC group (n=6), received intraportal escitalopram (2 μg/kg/min) during P2; H-ESC group (n=7), received intraportal escitalopram (8 μg/kg/min) during P2. Data are mean ± S.E.M.