Figure 1.

An in silico screen for transcription factors that direct formation of glia. A, Grayscale drawings are schematic views of glial progenitors in the developing spinal cord. At E13.5, glial progenitors are sequestered within the ventricular zone. At P0, these progenitors have migrated throughout the gray and white matter of the spinal cord. B, Color micrographs: three representative examples of transcription factors from the Mahoney database that show spatial/temporal expression patterns consistent with a role in specification/maturation of glia. C, Example of a transcription factor with a predominantly gray matter expression pattern at P0. For details, see Results.