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. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Neurosci Res. 2009 Apr;63(4):288–293. doi: 10.1016/j.neures.2009.01.003

Figure 3. Editing does not alter other pharmacological properties of the α3 subunit.

Figure 3

The allosteric modulators indicated were co-applied for 5 sec with either 3 μM (α3-Iso314) or 6 μM GABA (α3-Met314). The peak current amplitude in the presence of the modulator was divided by the response to GABA alone and multiplied by 100. The dashed line represents the response to GABA alone (100%). None of the responses were significantly altered by the point mutation.