Table 1.
Series | Name | Daily H2O Intake, ml | Daily NaCl Intake, meq | Daily I− Intake, μg | Daily Dietary Intake |
---|---|---|---|---|---|
1 | Effect of I− intake on pendrin abundance | ||||
Low-iodide content | 9.0 | 0.78 | 0.9 | I−-deficient, synthetic diet: 3.2 g/day, AIN-93M, cat. no. 520000, Zeigler Bros., Gardners, PA, 89 mg/day gelatin, 0.32 g/day sucrose | |
High-iodide content | 9.0 | 0.78 | 13.0 | ||
2 | Effect of H2O intake on pendrin abundance | ||||
High water content | 9 or 13 | 0.78 | 12 | Grain-based diet: 3.2 g/day, Zeigler Bros., 53881300, 99 mg/day agar | |
Low water content | 4 | 0.78 | 12 | ||
3 | Effect of vasopressin on pendrin abundance | ||||
Vehicle | 6 | 0.87 | 6.9 | Grain-based diet: 3.5 g/day Zeigler Bros., 53881300, 379 mg/day gelatin | |
dDAVP | 6 | 0.87 | 6.9 | ||
4 | Effect of H2O intake on pendrin abundance when circulating vasopressin levels are clamped | ||||
dDAVP+high water content | 11 | 0.87 | 6.9 | Grain-based diet: 3.5 g/day, Zeigler Bros., 53881300, 379 mg/day gelatin | |
dDAVP+low water content | 5 | 0.87 | 6.9 |
dDAVP, [deamino-Cys1, d-Arg8]-vasopressin acetate salt hydrate.