Table 6.

Serum Na⁺ and Cl⁻ concentration and Cl⁻ clearance in wild-type and pendrin null mice receiving dDAVP with a high H₂O intake (vasopressin escape)

	Na+, meq	Cl−, meq	Cl− Excretion, meq/24 h	Cl− Clearance, μl/min
Wild-type	126±2 (n = 4)	104±3 (n = 8)	0.700±0.08 (n = 8)	4.62±0.50 (n = 8)
Pendrin null	118±4 (n = 3)	88±3*(n = 5)	0.680±0.09 (n = 5)	5.46±1.03 (n = 5)

Values are means ± SE. Mice were given dDAVP by minipump and consumed the grain-based diet and 5 ml H₂O/day for 3 days, 11 ml H₂O/day for the next 7 days, and then killed (series 4, vasopressin escape).

^*P < 0.05.