Fig. 1.

Schematic representation of the behavioral protocol used to induce social stress voiding dysfunction. The identification of aggressive C57 males from a population of retired breeders was made by observation when these mice were placed with a 6-wk-old FVB male. C57 mice were deemed aggressive if they attacked the FVB mouse in under 5 min. Approximately one-third of C57 mice screened met this criteria. Mice were separated as soon as any bite resulted in bleeding.