Fig. 4.

Representative in vivo cystometrograms from control (A) and stress (B) mice show a higher volume at micturition that was characteristic of the stress group. With social stress, the volume at micturition nearly doubled from 88 to 179 μl with P < 0.01 (C). There were no differences in micturition pressure or the threshold pressure at which voiding was initiated. It was noted that in the stress group, the voided volume exceeded the infused volume by 13% ; in contrast, in the control group the voided volume was 10% less than the infused volume (D). While this difference did not reach significance, it does suggest that the prolonged bladder retention induced by social stress may have resulted in postobstructive diuresis. These bar graphs represent means ± SD of cystometry recordings from 8 stressed and 7 control mice.